Tyrosine kinases are important mediators of the signaling cascade, determining key roles in diverse biological processes like growth, differentiation, metabolism and apoptosis in response to external and internal stimuli.Recent advances have implicated the role of tyrosine kinases in the pathophysiology of cancer.Though their activity is tightly re
Abstract The occurrence of whole-genome duplication or polyploidy may promote plant adaptability to harsh environments.Here, we clarify the evolutionary Pop Pin relationship of eight GhCIPK6 homologous genes in upland cotton (Gossypium hirsutum).Gene expression and interaction analyses indicate that GhCIPK6 homologous genes show significant functio
In a variety of neurons, action potentials (APs) initiate at the proximal axon, within a region called the axon initial segment (AIS), which has a high density of voltage-gated sodium channels (NaVs) on its membrane.In pyramidal neurons, the proximal AIS has been reported to exhibit a higher proportion of NaVs with gating properties that are "right
BackgroundThe Policosanol Norway rat (Rattus norvegicus) is the principal reservoir for leptospirosis in many urban settings.Few studies have identified markers for rat infestation in slum environments while none have evaluated the association between household rat infestation and Leptospira infection in humans or the use of infestation markers as
The incidence of seborrheic keratosis (SK) generally increases with age Sterilisation Consumables and are mostly localized on the trunk, face and neck, especially on sun-exposed areas.The association between SK and skin malignancies appears to be accidental, but in situ transformation occurs more frequently in sun-exposed areas.Histopathological ex